Tuesday, January 17, 2006

Lipitor safe at high doses

Pfizer Inc. on Tuesday said a review of 49 clinical trials showed the highest dose of cholesterol fighter Lipitor was as safe as a placebo and as safe as the lowest dose of the top selling medicine in avoiding side effects, including potentially fatal muscle breakdown. The analysis is published in the current edition of the American Journal of Cardiology.

Physicians may prescribe a high dose of Lipitor to drop LDL cholesterol to a particular target. The PROVE IT trial gave us new targets.

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